Gut Stress Webinar

Dr. Shawn Talbott (Ph.D., CNS, LDN, FACSM, FACN, FAIS) has gone from triathlon struggler to gut-brain guru! With a Ph.D. in Nutritional Biochemistry, he's on a mission to boost everyday human performance through the power of natural solutions and the gut-brain axis.

Here is the webinar recording from the “Gut Stress” webinar that we did with the Certified Mental Wellness Coaches (CMWCs) – and the article with all the details.

The audio transcript is pasted below so you can follow along with the discussion.

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Dr. Shawn Talbott: Alright. There we get the recording going. Hey? Nice to see everybody. I’m gonna talk tonight a little bit about stress in the gut and I’ll explain that in a second. But let me do now that we’re recording, let me do a couple of housekeeping things.

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Dr. Shawn Talbott: Linda wanted me to mention. Let me see, please mention a participant that over the next week or so they may be getting an email from canvas. So canvas is the is the learning platform that this whole course goes through. So you may be getting an email from canvas, asking them to verify their email address

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Dr. Shawn Talbott: doing so will ensure that they’re getting announcements that I that I post in canvas. So when I post in the discussion section, you should get you should get a a maybe not the discussion section. Unless you’ve unless you’ve put a question in the discussion section, you’ll get notified when I put an answer there when I post something in the announcements like an announcement that you know the next webinar will be Monday night at 6 Pm. Eastern time like this one.

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Dr. Shawn Talbott: Everybody who’s in there, everybody who’s provided an email to get into the course should get an announcement on their email saying the next webinar is here, or any any other announcement that I post some people aren’t getting them. And so maybe they’ve changed their emails since they, you know, signed up for the class to the the, you know, the email that they’re using now. So we just wanna make sure that everybody’s getting that you can always log into canvas in order to see any of those new announcements or participate in the discussions. So you don’t have to. You don’t have to get an email announcement to do that kind of stuff. You can always just go straight in there

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Dr. Shawn Talbott: and then please remind participants that the zoom link for all webinars is always the same, and that the link is found in the course area. So if you just go into the like, the main home page for canvas just a little bit down. You’re gonna see the zoom link, and you click on that, and it opens this. So

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Dr. Shawn Talbott: some people might be watching this on replay. Some people might be watching this on Youtube, but you know, make sure that you that was a nice little cameo there. We we always liked that kind of stuff. Alright. So there’s the housekeeping stuff.

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Dr. Shawn Talbott: And I wanna talk to you guys. So I posted an article about stress and the gut in the discussion area. So you guys can go read the article there. It’s also posted up on my blog in case you have people that don’t have access to canvas. You know that you wanna share this with you can just copy that link from my blog and share share that out. And it’s based on it’s based on a new study that came out. And I’m gonna share my screen in just a second. But when did. This study can’t come out. It came out

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Dr. Shawn Talbott: just like 2 or 3 days ago. I put in the article. I put the

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Dr. Shawn Talbott: I put the date. I think it was what is today. Today’s the 20 ninth. I think this study came out on the 20 third. So it’s really, really recent. And what they did was, let me share my screen so I can show you this really cool, graphical.

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Dr. Shawn Talbott: abstract

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Dr. Shawn Talbott: can everybody see that right now? It’s like a little picture of mice and gut cartoons. Okay? So what they did. So the basis for this study was, we’ve known for a long, long time that if you have a lot of stress psychological stress, right? You’re stressed out by your job, you’re stressed out by a relationship. You’re stressed out by a deadline. Whatever the case, whatever’s stressing you out

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Dr. Shawn Talbott: that can cause gut problems right? If people who have irritable bowel syndrome have more symptoms right, they have more diarrhea or constipation or gut pain, or something like that.

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Dr. Shawn Talbott: People with inflammatory bowel disease will have more symptoms when they have more psychological stress. We see more gut symptoms in people with those conditions. If they are sleep deprived, which is a very unique type of stress on the body, you know, we could count that as as a unique type of of psychological stress.

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Dr. Shawn Talbott: And so what this group a group of Chinese researchers was trying to figure out was, okay. We’ve observed this for a long time. Right? The gut brain axis signaling. Something bad happens in the brain. Something bad happens in the in the gut. The second brain.

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Dr. Shawn Talbott: But wh! What is that? Is it? Just a nervous system thing, you know, is it? You know? Vagal nerve.

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Dr. Shawn Talbott: you know stimulation? Or is there actually something going on in the gut a few years ago, maybe more than a few years ago. Now maybe.

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Dr. Shawn Talbott: maybe I don’t know.

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Dr. Shawn Talbott: 5 or 6 years ago. There was a really cool set of studies done at Ucla University of California, Los Angeles, in the lab run by Emerin Meyer.

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Dr. Shawn Talbott: who’s a good friend of mine who did, did. Did. A video with me that’s posted in the in the video section of the of the canis canvas learning module. He’s one of the top, you know, gut brain access researchers out there. His lab showed that you could

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Dr. Shawn Talbott: cause psychological stress, and that would lead to gut problems. But it would also very uniquely lead to

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Dr. Shawn Talbott: changes in the microbiome changes in what bacteria grows. So sort of like, you know, short version of the story is that the more psychological stress you have, the more that it changes the bacteria in your gut that grow. So you grow more sort of bad bacteria that are more inflammatory in nature and less good bacteria that are anti-inflammatory, but also produce the feel-good signals right neurotransmitters and things like that so stress in the brain leads to stress in the gut.

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Dr. Shawn Talbott: But what was really interesting is that now you have this stressed gut that now is sending stress signals back up to the brain. So you get into this very vicious cycle of a stressed out brain leading to a stressed out gut leads into a more stressed out brain and a more stressed out gut. And you need to go in and short circuit that somehow either short circuit it at the level of the gut.

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Dr. Shawn Talbott: maybe with probiotics, maybe with things that improve gut integrity like prebiotics, etc., etc., or maybe with relaxation, modalities right to reduce the stress in the in the brain. There’s all kinds of ways that we can do it.

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Dr. Shawn Talbott: This study took a little bit more of a biochemical approach. And what you see on the screen right now is what’s called a graphical abstract. So with research studies, there’s a written abstract where they you know in words. They say, this is why we did this study.

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Dr. Shawn Talbott: This is what we did. This is what we found the results. And this is our conclusion. And nowadays a lot of journals are starting to do these graphical abstracts. So in one little cartoon, it sums up exactly what was done and what they found, and all that kind of stuff. So I’m I’m only going to talk about this, which is. And they did this in mice.

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Dr. Shawn Talbott: Sometimes people get kind of, you know, Iffy, about about animal research. Sometimes you have to do animal research, because, you know you have to do. You have to really get in there and look at the tissues right? What is cool about this is that they did the animal research

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Dr. Shawn Talbott: in mice, and then they corroborated it. They found out the same exact thing in humans. And I’ll I’ll step you through all of that. So they stressed out the mice. There’s all kinds of ways to stress out mice. You can. You can give them a little electric shocks. You can make them swim. You can keep them up at at

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Dr. Shawn Talbott: in the daytime, when they’re usually sleeping. Mice are nocturnal, so they’re usually awake in the in the night, and then they sleep during the day. So if you wake them up during the day, that can that can stress them out. So they stress them out. When you have let me see if I can get my cursor here, when you have psychological stress in the brain.

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Dr. Shawn Talbott: it activates the sympathetic nervous system. This is the fight-or-flight reaction. Anytime, we have sympathetic activation that is going to send signals from the brain in the head through the nervous system down to the brain, in the gut, the second brain. And that changes the microbiome right? We’ve we’ve observed this before. We’ve seen changes in Lactobacillus, changes in bifurbacterium changes in all sorts of

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Dr. Shawn Talbott: families or or genuses of bacteria. So they they found that they found that specifically this strain.

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Dr. Shawn Talbott: Lactobacillus Muranas, which is just basically mouse Lactobacillus. That increased. And so that in and of itself isn’t

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Dr. Shawn Talbott: necessarily a good or bad change. It’s just that the microbiome change. We generally think of Lactobacilli as being one of the sort of good classes of bacteria. But even too many of a good thing can be a bad thing, because this species in general, what it does is it makes this compound

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Dr. Shawn Talbott: ia, which is a which is a specific indo. What is the actual name of it? Indel 3. Something or other? Let me see what I put in the article.

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Dr. Shawn Talbott: Where is IAA

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Dr. Shawn Talbott: IA

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Dr. Shawn Talbott: is.

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Dr. Shawn Talbott: It’s somewhat indo. 3 acetate, that’s what it is. So these indoors again aren’t necessarily good or bad, but this particular, and so, in fact, some indoors that you can get from things like

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Dr. Shawn Talbott: Broccoli and Cauliflower and Brussel sprouts and things like that in small doses can actually be a really really good thing. They have some anti-cancer properties. But this indole what it does when it’s too high is it prevents these very specialized intestinal cells called intestinal stem cells from

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Dr. Shawn Talbott: being protective right? These are stem cells, that when they’re if they’re activated the right way. They can protect your gut lining from damage. They’re involved in the overall

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Dr. Shawn Talbott: process of homeostasis, maintaining balance at the level of the gut. So you could think of these is intestinal stem cells as being preventative for leaky gut.

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Dr. Shawn Talbott: But this ia, this i aa, this indo, prevents that from happening. So if Ia is too high. It prevents these cells from being protective against leaky gut, and the result of that is that you end up getting leaky gut. They found that the reason that it does this, where’d my cursor go?

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Dr. Shawn Talbott: Here we go. We’re back is because it interferes with mitochondrial bioenergetics. So this this is really cool, because I’m studying this right now potentially to develop an anti-aging

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Dr. Shawn Talbott: kind of a kind of a dietary supplement from the perspective of the microbiome. So the mitochondria are these? They’re they’re kind of like microbiome cells, right? Because they used to be bacteria millions and millions of years ago. They were bacteria and some cell decided to engulf them.

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Dr. Shawn Talbott: and that bacteria which is now a mitochondria, is the organelle inside of cells that generates our energy. So anytime we need energy, cellular energy. Our mitochondria is the thing that’s doing that mitochondria can burn sugars. They can burn fats. They’re they’re the they’re the powerhouse of the cell. And so the microbiome

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Dr. Shawn Talbott: talks to your mitochondria. And this is really really cool, because this potentially means that we can harness the microbiome

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Dr. Shawn Talbott: to get the microbiome or get the. We can use the microbiome to get the mitochondria to burn more fat.

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Dr. Shawn Talbott: to generate more energy, to give us better endurance, to to do all sorts of wonderful things, and anybody in anti-aging research looks to the mitochondria as the secret to anti-aging research. If you can keep the microcontroller, if you can keep the mic. If you can keep the mitochondria young and doing its job efficiently, you can keep the cell young, and if you can keep the cell young. You can keep an organ young, and if you can keep an organ young.

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Dr. Shawn Talbott: you can keep the whole organism the whole, the whole creature young, and so a lot of anti-aging therapies work at the level of the mitochondria. But what the new research is suggesting is that

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Dr. Shawn Talbott: that isn’t the root cause of the aging process. It’s one level below that which is the microbiome, and that’s really cool, because, as we’ve talked about here many times in this class, we can. We can change the microbiome very, very readily with food, with the fibers we eat, and the fermented foods, and the flavonoids and

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Dr. Shawn Talbott: etc., etc. So you know, by doing all the things that we do at the level of the microbiome to improve mental wellness as mental wellness coaches. We’re probably also able to harness the microbiome, to change what the mitochondria are doing, and therefore change the rest of the body in terms of in terms of, you know energy energy

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Dr. Shawn Talbott: handling if you want to put it that way. Okay, so the other thing that they did in here that was really cool is they intervened here. Right? So they knew that psychological stress was gonna cause this range of metabolic derangement, right? I so psychological stress change in bacteria in the microbiome

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Dr. Shawn Talbott: changing its metabolism. This over production of that specific endole, that indo interferes with mitochondrial bio bioenergetics that leads to these problems in in in gut integrity, right so they say, epithelial injury here.

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Dr. Shawn Talbott: that’s the same thing as Leaky Gut. So they stopped that they prevented that leaky gut from happening by giving this in the lower right hand corner. This is this is a dietary supplement called Alpha ketoglutarate and this is kind of a blast from the past, because back in my sport nutrition days. Alpha Ketoglut was one of the hottest nutritional supplements out there because it helps the mitochondria

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Dr. Shawn Talbott: because it helps the mitochondria it helps with energy and stamina and endurance and fat burning and and even even

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Dr. Shawn Talbott: doesn’t really help with muscle growth, but it can help with preventing muscle loss. So a lot of athletes would take it, especially at night, to make sure that they weren’t breaking down their muscles so it could keep their muscles in an anabolic state versus a cat, which is a building state versus a catabolic state, a breakdown state. So it’s a it was a for years. It was a really popular

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Dr. Shawn Talbott: sport nutrition supplement nowadays. It’s a really popular anti-aging supplement for the reasons that I just said, if you can use a supplement like this to maintain the energy production qualities of the mitochondria.

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Dr. Shawn Talbott: It lets the cell function better, lets the organ function better lets the organism function better. So. A lot of sort of anti-aging biohacker people supplement with Alpha ketoglutarate in a similar way that you know the athletes used to do it years ago, so this could potentially be something that would make it into an anti-aging supplement that we would have

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Dr. Shawn Talbott: that works across the microbiome and the and the mitochondria. So this is all great. You’re probably thinking, well, big whoop who cares about stressed mice? Right with, you know, great for the mice to be stressed out and get these gut problems and these microbiome problems. But they found the exact same thing in humans. They didn’t do the same study. They just took

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Dr. Shawn Talbott: fecal samples right. They took poop samples from people to measure their microbiomes. And what they found was that the the levels of this indo were higher in people that were stressed out and had major depressive disorder. Right? So there’s the human link right there, right? The same thing that we’re observing in these mice

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Dr. Shawn Talbott: seems to also be true in humans that are suffering from those problems being high stress and being and being depressed versus a versus a normal, a normal, normal sort of cohort, so that I’m not going to go through all the supplements that I recommend. But if you go check out that article, even either in the discussion. Section

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Dr. Shawn Talbott: of canvas or on my blog. Bestfutureu.com you’re gonna see? You’re gonna see like my article, that kind of summarized what I what I just said. And then you’re gonna see a list of it says, what else can we do? In addition to Alpha ketoglutarate? What other supplements can support mitochondrial bioenergenics, and I list a whole bunch of them.

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Dr. Shawn Talbott: Some of them you maybe have heard before. Some of them might sound a little little exotic if you’re into the anti-aging world at all. Some of these are gonna look very familiar things like carnacine, alphilopoic acid, an acetyl cysteine acetyl carnitine Pq. Coenzyme, the ones that will be very familiar to you, though, as as a as a student in this class are polyphenols

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Dr. Shawn Talbott: which I talk about a lot be complex vitamins, magnesium

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Dr. Shawn Talbott: omega, 3 fatty acids, and there’s a whole list there and then in the article I also have a an abstract from a study that just came out 2 days ago, 2 or 3 days ago

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Dr. Shawn Talbott: about the Mediterranean diet. And so what I write about is that, hey? There are ways that we can get a lot of these nutrients in our baseline diet and the Mediterranean diet, or the mental fitness. Diet is a great way to do that, so that if you’re eating a diet that’s high in fruits and vegetables, whole grains, fatty fish.

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Dr. Shawn Talbott: brightly colored fruits and vegetables, seeds and nuts and lean proteins and things like that. You’re gonna get amino acids. You’re gonna get fatty acids. You’re gonna get polyphenols. You’re gonna get if you include, you know, fermented dairy you’re gonna get, you know, from Yogurt or Kefir, or something like that. You’re gonna get all those those fermentation products that we’ve talked about here. And so you’re gonna get all the kinds of nutrients

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Dr. Shawn Talbott: from a Mediterranean diet or a mental fitness diet that are going to do exactly what we just talked about here. They’re going to be able to prevent that that those stem cells from sort of becoming dormant or becoming blocked. You’re going to amplify the bioenergetics of your mitochondria. You’re going to maintain the diversity of your microbiome so that you know one species doesn’t predominate and start over producing

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Dr. Shawn Talbott: these, these, these sort of stress markers. But what this study that just came out a couple days ago looked at is they looked at the adherence among university students for

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Dr. Shawn Talbott: staying on the Mediterranean diet. So they basically went to these university students. How many did they do? A lot? 750 students. And they asked them to follow a Mediterranean style diet.

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Dr. Shawn Talbott: And this was these weren’t American students, these were students in Turkey. So you think you would think that they would be more inclined, maybe, to eat a diet like that, because that’s kind of the way that they

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Dr. Shawn Talbott: are traditionally eating in that part of the world. Unfortunately, they didn’t adhere. Very well, let me see here, most students, 59.2% had poor adherence to these Mediterranean diet recommendations, and as a result of that they were able to sort of grade the level of of adherence. And what they found was. And this might sound pretty obvious to you guys because we’ve talked so much about Mediterranean diet. In this course.

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Dr. Shawn Talbott: those who adhered more closely to it had much lower rates of depression, stress and sleep problems and those who had lower adherence right? They were eating more junk food and less Mediterranean diet. They had more stress and more depression and more sleep problems. And those are the main outcomes that they looked at in this study which makes perfect sense. But you know, it just goes to show. If if we get the right things in our diet, whether it’s from supplements or whether it’s from the baseline diet.

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Dr. Shawn Talbott: it’s gonna change our metabolism like what I talked about here, and it’s gonna help us feel better in in in in a variety of different ways. Okay, so I’m going to do this I’m going to stop to share. Are there any questions about that? I just thought it was kind of a cool. If you guys want the actual studies. If you go to the articles that I posted, there’s links there and you can go and you can click. And you can get the actual studies. Or you can, just you can just get the summary article if you want to. Are there any questions about that

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Dr. Shawn Talbott: or comments

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Dr. Shawn Talbott: or anything?

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Dr. Shawn Talbott: Okay, Mary, you put your hand up.

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Dr. Shawn Talbott: Go ahead.

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Mary Nelson: I I’m just kinda wondering how many years out are you from developing something like that cause I take, I take something that has mitochondrial support and a lot of other DNA and stem cell report support that I love.

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Mary Nelson: but it does have point 7 5 milligrams of melatonin in it in the night, in the night when. And so I was like.

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Mary Nelson: I need to get Dr. Talbot to create something like this, so I don’t have to take the one that has melatonin in it. Melatonin is actually one of the one of the main antioxidants inside of mitochondria, and that’s that’s one of the reasons that it’s probably in that supplement that you take. I wouldn’t point 7 5. Not too bad. I mean it. It’s not a lot. But

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Dr. Shawn Talbott: yeah, it’s well, that’s the that’s the question. You know, if you’re we know that that the standard dose of melatonin is not good right? And that’s usually 3 milligrams. So whatever the percentage of that is, it’s you know, it’s it’s less than a third. So someone can probably do the math here. We’re probably talking about 20

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Dr. Shawn Talbott: 20 of the of the normal dose. Is that enough to start getting your body to shut off its own production?

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Dr. Shawn Talbott: II don’t know. And is it? Is it worth it to, you know? Maybe risk that to have these other nutrients that are protecting your mitochondria? It’s

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Dr. Shawn Talbott: maybe a fair, maybe a fair trade off. Yeah. But I think, like, you know, one of the things that gets me excited is that the whole world of anti-aging medicine has been chasing this for a long time, and and it seems like the world of mitochondria and the world of microbiome are coming closer and closer and closer together in terms of like.

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Dr. Shawn Talbott: how they talk to each other, and how they send. You know how they communicate across the whole body. So it’s getting is getting super super exciting. It’s also getting getting problematic to talk about it, because it’s hard to say microbiome and mitochondria

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Dr. Shawn Talbott: without messing them up. So go ahead. Go ahead, Dana.

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Dana Lewis: I have a question that I maybe is off topic. But as we’re talking about Melatonin, and we’re talking about anti-aging when my husband had cancer. One of the very first things

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Dana Lewis: functional doctor told him, was start taking melatonin like, take 3 milligrams of melatonin in the morning. Take 3 milligrams of Melatonin at night, like your body needs that. And they explained it as like a building block for fighting. The inflammation in the cancer like, does that make any sense?

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Dr. Shawn Talbott: Melatonin wouldn’t be my first one to do like. So it it it is an antioxidant like we just talked about. But there’s there’s, I think there’s better ways to induce an antioxidant response and an anti-cancer response. You know, things like things like like catechines that come from green tea or or the or the Flavonoids the curcuminoids that come from turmeric. In fact, those 2 would probably be my first ones, because what they do really really well

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Dr. Shawn Talbott: is they activate this process inside cells called the nerf 2 pathway that produces your body’s antioxidant enzymes, things like glutathione and superoxide, use mutase and catalase, and all those kinds of all those enzymes are literally a million times more powerful

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Dr. Shawn Talbott: than an individual melatonin or an individual vitamin c, or an individual vitamin e, so those are all, maybe still important to having small doses in supplements. But it really is these flavonoids that activate the cell’s own internal

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Dr. Shawn Talbott: disease fighting

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Dr. Shawn Talbott: qualities. Right? So those are. Those are more. Those are more what I would. What I would

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Dr. Shawn Talbott: gravitate towards, I think, yeah, cool. Thank you.

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Dr. Shawn Talbott: Yeah, of course. Alright. So that was it. That was only 24 min. So now we have the whole rest of the hour to answer questions. If you guys have them

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Dr. Shawn Talbott: any questions. In fact, you know, Todd, I see you there. You had posted something about Hashimoto’s and I need to answer this for somebody else, too. So maybe I’ll just maybe I’ll just take a crack at that. Do you mind? So I don’t have to go open up another window. Do you mind telling me what what the question was again?

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Katy & Todd Randall CMWC: So, my friend, she has Hashimoto’s, and she loves to work out, and so when she works out, though she says she gets really bad, aches, pains her. Her throat will swell up, and she’ll actually get feverish from it.

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Katy & Todd Randall CMWC: And so she just kind of sent she had this general post out like, anybody know anything that can help? Yeah, so so do you happen to know if she’s I is she? Is she taking thyroid hormone? I would assume.

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Dr. Shawn Talbott: I would need to ask her. Yeah, that I guess I should have asked her. So sometimes people who have Hashimoto’s if they’re if they’re not taking thyroid when they exercise, they get really, really tired. They get like it’s like they they get completely wiped out from their exercise.

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Dr. Shawn Talbott: More more than you would expect. Right, you know, exercising supposed to make you tired in a sense. You know it’ll it’ll energize you for a period of time. But a lot of times people who have those thyroid issues. They they’ll they’ll be very, very fatigued after a after an exercise bout

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Dr. Shawn Talbott: and they might be they might be tired in general, because they they are. They are hypothyroid. Their thyroid levels are low.

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Dr. Shawn Talbott: Having low thyroid can lead to a wide range of metabolic problems. They could have blood sugar problems. They can be gaining weight they can be. They can feel tired all the time. They can even sometimes feel like almost

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Dr. Shawn Talbott: almost panicky so it could be like some of what she’s describing could be. It could be just that that she’s low in thyroid, and she needs to get her thyroid levels up

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Dr. Shawn Talbott: one way to do that. So I think the other part of your question was, do we?

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Dr. Shawn Talbott: Do we have any ingredients in

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Dr. Shawn Talbott: Do we have any products in the Amari product line that will help with thyroid. And the short answer is, we don’t have anything that helps directly. Doing a supplement that helps the thyroid is is is really pretty difficult, like you can do things like iodine, and things like that, that the thyroid needs but the best way to help. The thyroid is to lower cortisol.

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Dr. Shawn Talbott: Because, cortisol, if it’s too high, body’s primary stress hormone that will interfere with thyroid function. And so what you want to do is you want to make sure that cortisol comes down so that the thyroid can do what it’s supposed to do. Okay? So that would probably be the best thing. So the the best

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Dr. Shawn Talbott: cortisol controller that we have Nmr is is mood plus. So that would be the like the most direct way.

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Dr. Shawn Talbott: an indirect way would be to do something like happy juice or fundamentals, or anything that could combine antibiotics, and meant to sync at the same time. And the reason for that is that a lot of thyroid problems, just like a lot of autoimmune system problems are because of leaky gut. And if we can solve the leaky gut problem. We’re getting to the root of what’s causing the immune system to be overactive.

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Dr. Shawn Talbott: Does that make sense?

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Dr. Shawn Talbott: Yeah, it does. Okay? So I go. I go mood plus, to begin with, as a direct cortisol controller, and then to solve the leaky gut, I would do some combination of products that has antibiotics and meant to sync.

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Dr. Shawn Talbott: okay, okay? And I’m gonna pause for a second. I’ve got something beeping over in the corner there. So I’m gonna

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Dr. Shawn Talbott: okay. I’m back hopefully.

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Dr. Shawn Talbott: Can’t remember where I put my glasses. Okay? So hopefully, hopefully. Hopefully, that helped with that. So sorry for the interruption. Who’s next? Mary is next. So go ahead and unmute.

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Mary Nelson: Okay, I have a question about our citric acid. I know it’s multiple supplements that we offer through the Amri and Kyani lines. Can you expand a little bit? Simply because

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Mary Nelson: I have someone who needs some support for her autistic son? And as an autism, mom, I’d like to give her suggestions of what has been great for us, but she thinks

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Dr. Shawn Talbott: her son has a citric acid allergy, which is odd to me. And then somebody else told her that a lot of times that sourced in the mold. But I know that there can be different sources from lots of places, so you can get it from corn. You can get it from wheat. You can get it from limes and lemons and other citrus fruits where most of it comes from is corn.

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Dr. Shawn Talbott: Sometimes there’s a there’s a mold that grows on corn that can also be extracted for citric acid. Basically, any plant source can be used as a citric acid source people get when they hear it comes from mold they get, you know, the first thing they do is mold. I don’t want any mold

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Dr. Shawn Talbott: doesn’t matter where you get the citric acid from the places we get it. We either get it from limes in some products at Amari, or we get it from corn. If we get it from corn, we get it from non-genetically modified corn, not from not from the mold that grows on corn.

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Dr. Shawn Talbott: If we got it from there it would be exactly the same, because when you purify it down, citric acid is citric acid is citric acid. It doesn’t matter where it comes from. It’s 100% pure citric acid. There’s no way you could even tell if somebody said to me. This is from limes, and it was actually from corn the like. I would do a Gmo test on it, just to just to make sure there was no sort of contamination, but they’re exactly the same

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Dr. Shawn Talbott: compounds when it’s when it’s pure. And you know, we analyze for all that kind of stuff. So there’s absolutely no difference between any of the sources.

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Dr. Shawn Talbott: If somebody thinks that they have a sensitivity to citric acid. I don’t think that’s a real thing, I think what they might have is a sensitivity to something that is along with the citric acid, because acids like you can’t have an allergic reaction to an acid if you have leaky gut, or you have an inflamed gut, or you have reflux, or something like that. Any of those fruit acids can be problematic, depending on what else they’re they’re they’re mixed with or complex with, does that make sense so far?

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Mary Nelson: Yeah. And that was, I mean it. It’s helping to hear you explain. But my gut instinct, when she said that was, I don’t think that’s what is allergies, too, and let’s not freak out about mold. And what I would say is like, there’s a there’s a lot of like misinformation on the Internet about citric acid whenever we launch a new product, and it has a fruit acid in it, you know. Sometimes it has citric acid, sometimes it ha! It’ll have malic acid or tartaric acid, or

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Dr. Shawn Talbott: you know whatever right and people get. II don’t know why this is. There’s, you know, there are people that say, Oh, it’s bad for you, for for some reason.

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Dr. Shawn Talbott: and it’s like that’s what makes fruit taste like fruit. Right? That’s what gives a tart taste, or a or a bright taste, or a you know if you’re trying to get a grape taste, you have to add tartaric acid, because that’s what makes grapes taste like grapes. So you ha! You have to have that kind of stuff if you want your food to taste the way the way you want it to, and there’s just absolutely no.

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Dr. Shawn Talbott: no problem with them whatsoever that said like, I don’t wanna deny that they had something once with citric acid or repeatedly with citric acid, and they didn’t do well with it. That’s not due to the citric acid. It’s due to something else, and that something else is very likely to be

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Dr. Shawn Talbott: inflammation in the gut, disrupted microbiome. Leaky gut. You know some of the things we’ve talked about here before, and if you can solve that problem, then like miraculously, they won’t have problems with citric acid anymore.

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Dr. Shawn Talbott: Okay.

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Dr. Shawn Talbott: thank you. Yeah. And I, you know I would. I would maybe go back and say, like, you know, Hey, you know, maybe try this, you know, gut rebuilding regimen, you know, that includes these probiotics and these prebiotics and that kind of stuff. And and and see how you go on that.

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Dr. Shawn Talbott: Okay.

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Dr. Shawn Talbott: all right, let me jump up here. There’s a few things posted in the in the chat. Let me go up here, and then I’ll and then I’ll grab Jazzy, who’s next and next in line.

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Dr. Shawn Talbott: let’s see. So Michelle is saying, I would love to understand natural caffeine better, especially with the new edge being launched. Caffeine does wire me, does natural caffeine react differently? Yeah, it might. So a lot of times when people have problems with caffeine. It’s it’s because of the way synthetic caffeine is metabolized in the body. So the so the big difference between synthetic caffeine which you’ll see on your labels either. If it just says caffeine, then it’s synthetic caffeine. Sometimes it will say

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Dr. Shawn Talbott: caffeine and hydras. That’s just also just another pure form of caffeine pure caffeine isn’t necessarily bad, except for the fact that it will be absorbed really quickly. That’s what that that’s in fact, sometimes a lot of companies want synthetic caffeine because it hits you really fast. You use the product and it goes boom, caffeine, right? You feel the energy very quickly

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Dr. Shawn Talbott: because it’s pure caffeine, and it’s it’s absorbed into the system very quickly. So you get it, you get an energy spike that is very steep.

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Dr. Shawn Talbott: You also get an energy drop off. That’s very steep, so your body metabolizes it very quickly, so most synthetic caffeine will give you a quick hit. But a quick crash or a relatively quick crash.

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Dr. Shawn Talbott: Natural caffeine. The the energy curve looks more like this. It looks more like a like a like an instead of an upside down. V. It looks like an upside down. U, because it comes on slower, but it lasts longer, and it goes away more gradually. So it’s not quite as quick of up, you know. Blow your hair back or not, my hair. But you guys get the idea.

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Dr. Shawn Talbott: But it also doesn’t give you a crash. It also doesn’t give you the jitters and the palpitations, and the irritability, and all that kind of stuff. So you’re trading off the quick hit

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Dr. Shawn Talbott: for longer, but also more more gradual and more sort of like a tempered kind of an effect. And the reason for that is that the natural caffeine isn’t just caffeine.

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Dr. Shawn Talbott: It’s mostly caffeine, but it comes along with some natural compounds. When we get it from green tea it comes along with sometimes theanine depending on how it’s how it’s how it’s processed. Atheine can relax you at the same time that caffeine is energizing you.

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Dr. Shawn Talbott: If we get it from green tea, it also comes along with the with the catechins that I just mentioned just a few minutes ago, which are antioxidants and those caffeine, those those catechans when they’re complex with the caffeine slowly absorption. So in this new edge product that we just launched.

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Dr. Shawn Talbott: we use caffeine from green coffee bean. So in that extraction you get a collection of polyphenols which slows the absorption. But you also get this. You get an acid called what is the name of the acid?

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Dr. Shawn Talbott: I’m completely blanking on the acid. Now I’ve been talking about it all week.

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Dr. Shawn Talbott: It’ll it’ll it’ll it’ll come back to me. I’ve been talking about it almost nonstop, and now, I’m now completely blanking on the name of this. But it’s

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Dr. Shawn Talbott: green coffee bean extract. Someone could probably Google it while I’m looking green coffee bean extract acid, and I’m a guarantee it’ll come up. That can help with blood sugar control. And so that’s another thing that you want. Sometimes, caffeine. If you have too much caffeine. It can mess with your blood sugar.

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Dr. Shawn Talbott: And so you don’t want that. This is a way to normalize that out, and having balance. Blood sugar will actually extend your energy even longer. So that’s the that’s the benefit there. And even sometimes people who feel like they’re very sensitive to caffeine can use natural caffeine and not not really have a problem. The last thing I wanna say, I was, gonna see if somebody had put it in the

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Dr. Shawn Talbott: I just see if somebody put it chlorogenic acid. That’s what it is. Thank you. Thank you. Adina. Yeah. Chlorogenic acid is really good for general blood sugar control, and then you get that sort of stamina effect.

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Dr. Shawn Talbott: The other thing about caffeine, though, that you want to avoid is that sometimes caffeine can increase cortisol in people. And so I’ve had some people say, Oh, I don’t do. I don’t do caffeine anymore, because I’m trying to lower. My cortisol

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Dr. Shawn Talbott: caffeine isn’t really a cortisol problem until you go above 400 milligrams. So you know, 100 milligrams. You can get the benefits of caffeine, 200 milligrams get the benefits. 300. You’re starting to get up close, but as soon as you get up to 400, that’s when you start getting into more of a cortisol over production, and you certainly don’t want to do that. So you could do this new product edge. Plus has 100 milligrams of caffeine in it, green coffee, bean,

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Dr. Shawn Talbott: edge.

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Dr. Shawn Talbott: One version of edge has 55 milligrams of caffeine from green tea

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Dr. Shawn Talbott: and those are the only places we have caffeine, at at least in the Amari product line. There are energy drinks on the market now that have 300 400 milligrams of synthetic caffeine in them, you know. So those absolutely would be cortisol bombs, and would cause like in me. Anyway, they would cause palpitations would probably make you irritated and

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Dr. Shawn Talbott: anxious, and you know all the bad stuff of caffeine. But little doses of caffeine actually have really good health benefits, small doses of caffeine like around that 100 200 milligrams are anti diabetic are anti Alzheimer’s help with fat metabolism, etc., etc. So you know, I think caffeine used at those small at those small doses can actually be a really good thing for a lot of people.

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Dr. Shawn Talbott: Okay, so hopefully, hopefully, that, answers the caffeine question, and then I’ll and then I’ll I’ll go to Jazzy now and then I’ll come back to the chat in just a sec.

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Jazzie Will: hey, Dr. Sean? Hey? Nice to see you.

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Jazzie Will: you, too. I actually have 2 questions. One, I have a family member that’s in her early seventies. She’s recently been diagnosed with congestive heart failure and a borderline and borderline aneurysm they put her on Jardians and some kind of a diuretic. She didn’t say what kind. She really wants to give the products a try. But she’s

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Jazzie Will: afraid nervous of, I know interactions, I mean anything like that. Is there certain ones you would recommend. Are there some that you would say? Absolutely not. She should not try.

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Dr. Shawn Talbott: No, I wouldn’t say I wouldn’t say there’s anything that would be would be definitely ruled out. I think whatever she tries she should probably start slowly, because with her body being under that that sort of stress, you know, you wouldn’t want to say like, here’s you know, here’s 10 products to start out with. But definitely, I would say that. But you know the things you’d be most interested in would be absolutely mental heart.

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Dr. Shawn Talbott: because if she has, if she has the, you know, heart failure, kinds of stuff, then that can help her heart be a much more efficient pump. That’d be absolutely the first one to try

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Dr. Shawn Talbott: after that it it probably doesn’t matter. It’s it’s a matter of like. Okay, does she want it? Does she want better mood, does she looking for, you know less stress? Is she looking for better sleep? Is she looking for, you know, etc., etc. Right? So you might. Do you know you someone like that? She might.

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Dr. Shawn Talbott: That is, someone who might want to stay a little bit on the lower caffeine side, you know, so she might not be a candidate for something like this new edge, plus that we just talked about right. It might be more like she would go antibiotics, or, you know, antibiotics and and edge, or something like that, staying on the staying, staying away from from stimulants.

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Jazzie Will: Perfect. Yeah, thank you. My next question is, I’ve been hearing a lot about methylated supplements. I know you have talked about our Vita Gbx and the importance, and I’ve heard you say, I think but I mean I might by be totally washed up. But I remember you at one stage, maybe saying that everybody should be on our Vita. Gbx is one of those under appreciated supplements, right? Because it’s

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Dr. Shawn Talbott: it.

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Dr. Shawn Talbott: prior to the all the research coming out around the link between the microbiome and mental wellness.

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Dr. Shawn Talbott: you know. And this is like, you know, last 10 years that that we’ve that we’ve had that data set, the data set. That was the next best before. That

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Dr. Shawn Talbott: was the link between micronutrients and mental wellness. So there’s a ho! There’s hundreds and hundreds of studies showing that if you’re low in B complex vitamins, if you’re low in, you know the major antioxidants C and E, and you know those sorts of things. If you’re low in d if you’re low in some of the essential minerals, you know, selenium and zinc and those sorts of things.

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Dr. Shawn Talbott: You are very likely to be more depressed, more anxious. Have an overactive stress response. Have problems concentrating, maybe not quite adhd, but definitely on that, on that spectrum. And so that’s that was state of the art before we learned all this stuff about microbiome. And so II hate that

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Dr. Shawn Talbott: that we’re kind of forgetting about that kind of stuff, right? That people are saying, you know, as exciting as the microbiome and the gut brain access is we can’t throw the baby out with the bathwater right? It’s still really important to get those baseline nutrients, in fact, right before the pandemic hit.

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Dr. Shawn Talbott: I was at a conference in London Nutritional Psychiatry Conference, and I presented some data about the microbiome right? Because that was the new big thing hitting right then. But there were. There were dozens of researchers from all around the world

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Dr. Shawn Talbott: showing their data, you know, and it was great because it was all in one seminar where a woman from South Africa got up and said, Here’s the data. Here’s the nutrition data in South Africa. And here’s how it’s linked to.

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Dr. Shawn Talbott: you know, mental well-being problems. And then somebody from Brazil got up and presented their data, and then somebody from France got up and presented their data and someone from Australia, and presented their data. And you could have superimposed it all right on top of each other, showing that across the board. Nobody was getting the levels of these basic nutrients, and because of that mental wellbeing problems read an all time high. And then literally.

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Dr. Shawn Talbott: I went home and the covid pandemic hit and and the world shut down right? So like, it is a really really important thing that if you don’t have those baseline nutrients. You can’t even run the pathways that make your neurotransmitters. So you know, you can have all the best microbiome in the world. But if it doesn’t have the cofactors to make that neurotransmitter metabolism run.

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Dr. Shawn Talbott: You’re you’re you’re gonna be spinning your wheels. And so methylated vitamins are a big part of that of that methylation process which is the process by which we convert amino acids into neurotransmitters. If you can’t run methylation, you’re you’re dead in your tracks. So Vita Gbx has all of that, all of that built into it so, and it’s just an easy thing for people to take every day with a like a meal

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Dr. Shawn Talbott: perfect. Thank you so much. Yeah, of course. Let me go. Let me go up here to Leanne.

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Leanne Weaver: Hi!

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Leanne Weaver: I have a question about mushrooms. I was talking about the new edge, plus and all excited about the lions main. And I had someone say, I’m gonna read it. So I don’t get. I’ve actually heard scary things about mushroom coffee mostly, and brain bleeds.

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Dr. Shawn Talbott: Do you know where that might have come from? Yeah. So some mushrooms lions made included? Can slightly thin the blood. So lots of things can thin the blood like omega threes thin. The blood polyphenols that I talk about all the time can thin the blood.

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Dr. Shawn Talbott: what else what else would be a good example? Turmeric can thin, thin the blood. So those are things where, if someone’s going in for elective surgery, I will sometimes say you know what. Hold off on those kinds of supplements just for a couple of days. Make sure your blood isn’t too thin, but you know it’s it’s like it’s a healthy thin, you know, but you don’t want that. If someone’s cutting into you right? So so there’s that

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Dr. Shawn Talbott: I think you’d have to take a heck of a lot of mushroom coffee to to cause an over an over thinning of your blood, you can pretty easily do it actually, with Omega threes like. If you took the Omega. 3 that we have at at Amari we have 2 Omega, 3 products. We’ve got sunset and we’ve got a product called Omega. If you were to.

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Dr. Shawn Talbott: If you were to

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Dr. Shawn Talbott: triple the dose of Omega, which is a pretty high potency. Omega. 3 supplement that would probably give a lot of people bloody noses it would if I doubled the dose. It would give me a bloody nose, for I have to double it for a couple of days, but it would thin my blood enough to give me a bloody nose so like there’s a

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Dr. Shawn Talbott: it’s like it’s like the Goldilocks principle, right? You don’t want your blood to be too thick. You don’t want it to be too thin. You want it to be sort of just right. That’s why we recommend 2 of those and 3 of the tiny little sunsets right? Because that’s in the sweet spot. But you could like you could overdose with with some of this goodness if that makes sense.

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Leanne Weaver: Yeah, thank you. Okay, yeah, sure, but I wouldn’t be. I wouldn’t be worried with

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Dr. Shawn Talbott: with this with this lions main extract you’d have to. You’d have to really take a lot of it to have a to have an excessive blood thinning effect. Yeah, okay, that makes sense. That’s what I thought. But thanks for the explanation. Yeah, no problem. Alright, Julianne, let me go to you in just a second. Let me go up here and see if there’s anything else in here.

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Dr. Shawn Talbott: What else can help with our cellular cleanup? So, Deirdre, the best thing we just talked about Vita Gbx vita Gbx can stimulate that nerve 2 pathway that I just talked about to help with antioxidant enzyme production, but it also stimulates the process of autophagy.

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Dr. Shawn Talbott: which is the cellular cleanup process. So Vita Gbx can do it, and then the other product can do. It is is super food and the ingredient super food that does it is a Japanese asparagus extract.

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Dr. Shawn Talbott: it stimulates the production inside cells of these compounds called heat shock proteins and heat shock proteins are the way that first of all, the cell protects itself from damage, whether that’s oxidative damage or inflammatory damage or or heat damage. That’s how they got their name

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Dr. Shawn Talbott: protect you from damage. But then some of that damage is going to slip through, and then heat chalk proteins will also clean up the residual damage that are there. So yeah, it’s like taking those Vita Gbx and superfood is like getting an internal cellular repair. Does anybody know and answer this in the chat? Does anybody else know the best dietary way to increase autophagy

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Dr. Shawn Talbott: or cellular cleanup.

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Dr. Shawn Talbott: You guys have all heard of it before.

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Dr. Shawn Talbott: Guarantee you’ve heard of it. But intermittent fasting. Very. That was quick. Good typing. Dana. Well done. Yeah. So so that that we can get that process by by eating the right nutrients.

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Dr. Shawn Talbott: And oh, yes, Don also also put fasting in there. Yeah. Awesome. Good job, you guys. So let me go to Julianne now.

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Julianne Muhlestein,CMWC: Sorry. Okay. So a a, a couple of questions. If it’s okay.

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Julianne Muhlestein,CMWC: my daughter really gets a lot of value from relief she her. She has her joint sublux, and she has just autoimmune pain.

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Dr. Shawn Talbott: and so she takes 3 in the morning and 3 in the evening, and then, if she’s really flirting up, she’ll even take more. Can we do? I know it says on there. 12. But if we’re doing that much regularly inflammatory or anti pain effect, so like you’ll you’ll top out. And that’s why we have 12 on there

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Dr. Shawn Talbott: problematic except for what I just said about blood thinning potential. That many can also give some people heartburn, because turmeric is a really sort of it’s a it’s a it’s a spicy spice. But if if someone’s taking 12 and they’re not getting the kind of relief that they are looking for I’ll say let’s switch it up a little bit and try something else to lower inflammation. So one of one of my favorite ways to recommend is that

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Dr. Shawn Talbott: I’ll have people take relief during the daytime, and then they’ll take either sunset or omega at night before they go to bed. And so both of those are anti inflammatory approaches, but they work on different pathways of inflammation, and so sometimes the the complementary nature of working on, you know, blocking, inflammatory enzymes and that kind of stuff with relief

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Dr. Shawn Talbott: is different than the the there’s these. There’s these inflammatory compounds called icosanoids, that if you can change those to to anti inflammatory ones versus inflammatory ones with Omegas. That sometimes can be the the thing that you need to get get it. Get get a handle on your on your inflammation and your pain.

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Dr. Shawn Talbott: Okay?

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Julianne Muhlestein,CMWC: Another question. Is there any help that we have for bile mal absorption?

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Dr. Shawn Talbott: So usually, when people talk about bio, it’s that they’re under producing bile. And that causes a problem with that absorption or causes malabsorption of fat is that is that maybe what they’re talking about. Maybe it’s I just got an email from a customer that was asking for help with that. And II wasn’t sure.

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Dr. Shawn Talbott: I honestly don’t know if if any, of what we of what we generally talk about here. So gallbladder problems are tough.

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Dr. Shawn Talbott: because once you’ve got a problem with your gallbladder and you have a problem with your bile production that so bile is your gallbladder squirts bile into your intestines to emulsify fats and make them easier to digest and absorb. And if you can’t do that, your fat doesn’t get emulsified. It basically the fat that you eat it’s it stays in a big glob, and therefore you have trouble digesting it. You have trouble absorbing it, and it leads to gastrointestinal problem. So bile is really really important.

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Dr. Shawn Talbott: Usually, if you have a good microbiome that can be effective at bile recirculation. So even though your gallbladder isn’t able to sort of store the bile as a reservoir and have it ready to go. Your liver is still gonna be making it. So if you have a good microbiome, it will recycle the bile back up, and it’ll go into the liver. And so you have a good cycle going on, even though you don’t have a storage depot for it in the gallbladder.

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Dr. Shawn Talbott: and I don’t know if that makes sense, but sometimes just making sure that the microbiome is diverse and resilient, will solve some of the bio problems

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Dr. Shawn Talbott: and does restore or digestive help. Yeah, yeah, I would say it would be restore, or digestive or antibiotics.

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Julianne Muhlestein,CMWC: All of that would be or

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Dr. Shawn Talbott: it it could be. And or, you know, so it’d be a matter of trying to figure out which which one to

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Dr. Shawn Talbott: which one to add. And when and maybe with someone like that, because a lot of times people with with bio problems have trouble with digestion in general. You might want to start with one. See how they do with it, and then add the next one, see how they do with it, and then add the next one versus, adding, all 3 at once.

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Julianne Muhlestein,CMWC: okay.

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Dr. Shawn Talbott: thank you. Alright. Yeah, sure. Alright. Let me go back up into the chat. Deirdre had another question up here. I should have answered all at the same time wondering about binders for toxins. We don’t have anything like that. And if if I ever recommend a product like there’s lots of products out there like, you know, clay products and

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Dr. Shawn Talbott: and like peat moss products, they’re they’re called something. All that peat moss stuff is called something.

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Dr. Shawn Talbott: anyway, I can’t. I can’t think of it right now. Zack Bush has a good product that is a binder product, so you could probably search his name. I can’t think of the name of his product anymore. It was called something, and then they changed the name of it. If anybody knows that you can put it. You can put it in the chat, and I can, I can tell you, if that’s the one that I recognize or not. Here’s what I here’s what I like about binder products like that, if you get like. If you get a clay or a Pete sort of based product.

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Dr. Shawn Talbott: it will do a good job of binding. If you have some nasty that’s in your gut that needs to get out of there. But it’s it’s nonspecific, meaning it’ll bind good stuff, too. So if you’re taking probiotics and you’re taking vitamins and you’re taking whatever else

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Dr. Shawn Talbott: it’s gonna bind that stuff, it’s gonna bind the vitamins and minerals from your foods. And it’s gonna it’s gonna take whatever out. Sometimes you need to do that. If you know there’s something bad in there that needs to go. Sometimes you need to do that for a few days, or maybe a couple of weeks, but then stop. It’s it’s not something you want to take on a long term basis.

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Dr. Shawn Talbott: I thought about, should we introduce a product like that at Amari? And I decided, no, because I was. I was afraid that people would buy it and put it on auto shipment and get it every single month, and be taking it every single month when it’s really something you want to take in a very targeted way. Take it. Now get rid of the thing, and then stop so that you’re not interfering with absorption of all the good stuff, too. Okay.

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Dr. Shawn Talbott: and let me look in. Let me see if anybody put that in there.

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Dr. Shawn Talbott: No, I don’t see that I can. If somebody has a question later and I get a chance to slide over, I can. I can. I can do a search and let you know what the name of that is.

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Dr. Shawn Talbott: Let me see if there’s anything else up here. I can answer while I’m in the chat. So if you’re allergic to mold

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Dr. Shawn Talbott: can our products cause cause issues? No. So you know, let’s let’s let’s say that I decided to use the that that mold it’s called Aspergillus niger. It’s a it’s a black mold that grow, it grows on cor, it grows on lots of things, but it grows. It grows readily on corn. Let’s say I decided to use that and extracted it down to citric acid and gave that to somebody

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Dr. Shawn Talbott: the the most mold allergic person wouldn’t wouldn’t know at all, because there’s no mold there. Right? It it would. It’s a it’s an it’s an absolute total non issue.

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Dr. Shawn Talbott: In fact, a lot of our products would would really help people with mold issues. Because mold issues. You know, you can go all the way down the the biochemical change of events, you’ve got mold. You’ve got immune system issues. You’ve got inflammatory issues. You probably have leaky gut issues. And then you can. You know all the products that we talk about. Not all the products, but a lot of the products we talk about are microbiome products, gut integrity products

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Dr. Shawn Talbott: anti inflammatory products, immune priming products, you know. So it goes all the way right back up the chain of events. And you know, so solves those issues and those sensitivities.

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Dr. Shawn Talbott: Okay, let me go to Jeanine now

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Jeanine Fusco-Lano: I love your background.

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Jeanine Fusco-Lano: And then the other thing is, I am noticing antibiotics. I love what it does for me, and II did go back on a little bit as a loft, but I’m noticing that even a half a scoop of antibiotics is like making me kind of groggy, and I know I can take energy to get that up, but I don’t want to be like doing up and down and all that. So you have any recommendations? Yeah, so so does anyone know what’s happening

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Dr. Shawn Talbott: with Janine? I’m gonna I’m gonna ask the group to to to diagnose your your your situation. What if somebody takes antibiotics and they get a little sleepy marcy? You got it immediately, Gaba.

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Dr. Shawn Talbott: So one of the neurotransmitters that is really accelerated in its production with antibiotics, is the body’s primary, relaxing neurotransmitter called gaba. And so sometimes people will use antibiotics at the end of the day

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Dr. Shawn Talbott: as a relaxation supplement because they’re really sensitive to that Gaba production. So Gaba goes up and cortisol goes down the end of a stressful day. That’s exactly what you want right. You want your stress to come down. So you’re more relaxed or or so you’re less stressed. And you want your gaba to go up. So you’re so you’re more relaxed.

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Dr. Shawn Talbott: yeah. So that’s what that’s what you’re experiencing right now, for, for whatever reason you’re really sensitive to it, it could also be. There’s a little bit of theanine in antibiotics, which is also an accelerator of of gaba production. So makes my body less tense like I don’t feel like I tensing up on it. So I like that during the day. Yeah, yeah, what you might want to do is maybe use antibiotics. Towards the end of the day.

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Dr. Shawn Talbott: So your body gets used to that, and I would guarantee you’ll still get like once your body gets accustomed to pre producing gaba when it needs to.

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Dr. Shawn Talbott: You, will. You’re you’re still gonna get the anti tension benefits. But you won’t get the sleepy benefits. Okay? So can I feel the anti-tension during the day. Can I feel the anti tension during the day, then? Yes, so so I would say. Use antibiotics towards the end of the day, until your body gets accustomed to it. So like, if it’s making you sleepy, take advantage of that right, take advantage of that over relaxation towards the end of the day, or right before you go to bed. Eventually, it won’t make you sleepy anymore, and you can shift it to the daytime, and you won’t get the sleepiness effects, you’ll only get the anti tension effects.

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Jeanine Fusco-Lano: Okay, alright, great. Thank you. It’s just a matter of your body getting used to that new found it for a couple of years, though. So, even though I’ve been on it, I’ve been on it for a few years. So that’s still the case. Oh, so no. So usually, that’s only a few weeks. II the way you asked the question. I got the impression that you were a new user. No sorry. No.

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Dr. Shawn Talbott: yeah, yeah. In. In in that case you might just be overly sensitive. So my sister in law is, is is is one of these people sensitive to Gaba, and it makes her theene makes her sleepy. This strain of bacteria, this lactose remnosis 11 makes her sleepy, and so she uses it at the end of the day. But

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Dr. Shawn Talbott: that’s the that’s the trade-off, I guess.

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Dr. Shawn Talbott: Let me see what what else we have in the chat here. So we talked about citric acid

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Dr. Shawn Talbott: chlorogenic acid. and

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Dr. Shawn Talbott: do the other edges have caffeine or natural caffeine. No, it’s just this new one. So the only places we have kids so watermelon edge no caffeine

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Dr. Shawn Talbott: grape edge. No caffeine. Just this new mango edge that we call edge plus has has the caffeine in it.

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Dr. Shawn Talbott: and on the energies. Energy, pomegranate lime has 55 milligrams of caffeine. But the dragon fruit is caffeine free.

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Dr. Shawn Talbott: Okay. let’s see.

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Dr. Shawn Talbott: let’s see, Julian’s got another question. How far away from meals for Gbx fit? Take it on an empty stomach, and then don’t eat until that’s a good question important to take morning versus evening. Does that matter? If not how from far from dinner? It doesn’t really matter.

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Dr. Shawn Talbott: Dinner, breakfast. It like time of day doesn’t really matter so much except from the standpoint that one of the benefits of Gbx fit is the appetite control aspect. And so, if you are one of those people that gets hungry during the day, and you need help with your appetite so that you don’t overeat during the day. Take it, or or earlier, rather than later. The reason we recommend that product to be taken

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Dr. Shawn Talbott: on an empty stomach is those 2 strains of bacteria seem to be more effective on an empty stomach versus with food. It’s not a black and white sort of a thing if you, if you can’t take it on an empty stomach, for whatever reason, and you have to take it with a snack.

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Dr. Shawn Talbott: That’s fine, too. It’s better to get it in your body than to not get it in your body. But the way that we recommend those 2 products is Gbx fit empty stomach, Gbx. Burn full stomach or or or with a meal? Okay, just to just to maximize the effects of those.

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Dr. Shawn Talbott: how much lions main is in edge plus a friend is taking a straight lines. Main supplement. And I’m curious how they compare so we don’t tell people that that’s part of our our secret sauce. If you, if you, if you want to call it that you know what we call our proprietary blend.

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Dr. Shawn Talbott: We keep that. We keep that kind of under wraps. If we listed it all out, then it’d be really easy for other companies to just go. Oh, there’s the recipe right there. I’m just gonna I’m just gonna copy that and sell it for $10 cheaper or something like that. So we don’t do that. And it it’s hard to compare sometimes product to product. So we’re using a a.

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Dr. Shawn Talbott: So our our lion’s main comes from organic fruiting bodies, right? Which basically is the is the above ground portion of a mushroom. When we talk about mushrooms, there’s the fruiting body, the part that we recognize as a mushroom, and then there’s a mycelium, which is the like, the root system, the underground portion.

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Dr. Shawn Talbott: Sometimes we want the mycelium of certain mushrooms. Right? So, shataki mycelium is really high in compounds that are good for the immune system. So we actually use that in in another product we use that in in seed, fiber in this case we want, we want the fruiting body. We want the above ground portion.

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Dr. Shawn Talbott: and we want organic, because mushrooms are really good at drawing metals and and and minerals and things like that out of the soil. So if we get organic. We have a much lower risk of getting, you know, problematic pesticides and all that kind of junk.

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Dr. Shawn Talbott: we want the fruiting body, because that’s where the compounds are that stimulate the the production of nerve growth factor which is good for your brain and good for the rest of your nervous system. Most lion’s main now, because it’s such a popular mushroom is

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Dr. Shawn Talbott: grown, is the mycelium that’s grown on corn in warehouses. We don’t do that. We get the fruiting bodies from Asia, where it originates. If you grow it on corn in a warehouse you’ll get something that you can call lions, May. But it’s let me go up here real quick and do

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Dr. Shawn Talbott: this. Okay.

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Dr. Shawn Talbott: if you grow it on corn in a warehouse, you’re gonna get something you can call lions main and put on your label, but you’re gonna get something that is low in the active compounds and high in starch. And it’s it’s lions main. But it’s not really gonna do anything for you. And so it’s hard to compare

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Dr. Shawn Talbott: product to product, not knowing where did they source it? How did they extract it? A lot of lions? Man isn’t even an extract at all. It’s just powder and a powder is gonna be a by definition is gonna be a low potency. So yeah, it’s hard to compare apples to apples sometimes when you’re when you’re looking at different products. And so it really comes down to.

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Dr. Shawn Talbott: We ask people to give the product a try and see if it lights up your brain, you know. Can you remember better? You know. Can you think more? Can you focus? Can you, you know, do do all the things that you want your brain to do? And and and if and if not, that’s that’s where the money back guarantee comes right, and I think I think every company should have should have something like that.

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Dr. Shawn Talbott: let me go and see if there’s anything else. Just a couple of comments.

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Dr. Shawn Talbott: Is relief, something that’s good to take every day it could be I don’t take it every day. I only take it when I’m sore, you know, so I’ll take it on days after I’ve had a hard workout like if I’m a little achy and stiff, and things like that, whereas my wife does take it every day. She takes it every day to help. She has a little bit of arthritis in her in her fingers, so she takes it on a on a daily basis. It’s like it’s like her every single morning, vitamin.

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Dr. Shawn Talbott: But it’s not. It’s not something that I take every day, because I because I don’t need it. I could. Somebody could argue with me, though, and say you should take it every day, because turmeric is such a wonderful anti inflammatory, and

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Dana Lewis: that’s what I wondered, like such this wonderful anti inflammatory that it can’t hurt but you, if you maybe you take it every day. If you have arthritis, you understand that it’s doing something cause you feel the difference. But if you’re taking it just to take it.

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Dr. Shawn Talbott: Yeah. Well, so so I could, I could make the other argument right? So now I would come in and say, yeah, you should definitely take turmeric every day. If you look at all the data population data, you know, big epidemiological studies. Turmeric taken every single day like, like, if it’s in, if it’s in your curry that you’re eating on daily basis, you have a lower risk for cancer, you know. So why, why wouldn’t you want that effect? You know it’s it’s also

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Dr. Shawn Talbott: it’s also the question of like, how many supplements can you take in a day? Right? Do we want? Where does term work fall? Yeah, it’s important. But for me, is it more important than my

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Dr. Shawn Talbott: antibiotics? Is it more important than my edge? Is it more important than my Vita Gbx? You know it probably falls for me, at least it falls down here somewhere, and so sometimes, I take it. you know more of a practical consideration.

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Dr. Shawn Talbott: Okay, let’s go back to Mary.

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Mary Nelson: Thank you. I’m so glad I remembered I needed to ask you this. So for a man who we’re noticing is having monthly breakouts in this region under the nose kind of

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Mary Nelson: and I wondered at first if it could be yeast related. But I’m wondering now, hormonal, because it’s a monthly thing. Is this something that is a men’s ignite would help, or that’s that’s interesting. So

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Dr. Shawn Talbott: is it’s like, it’s like, monthly, like, almost like like a like a woman would say, it’s like period acne. Yeah. Like for the past, probably 5 or 6 months. So it’s it’s definitely become a monthly. Yes, so I wonder? So can I ask, is he is he overweight at all? No interesting

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Dr. Shawn Talbott: I don’t know. That’s a good question.

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Dr. Shawn Talbott: If you were so, the reason I asked for overweight is that sometimes overweight men will have will be estrogen dominant right? So they’ll have. Their testosterone will be fine, but their estrogen will be really high, and that can lead to some of those things that you know, it makes it hard for them to lose weight, cause their testosterone is, you know, either high or a little bit low, and their estrogen is either normal or a little bit high.

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Dr. Shawn Talbott: and either product could help them at that point, either the the and they’re not gonna want to take the women’s product, right? They’re gonna be like, I don’t want. I don’t want that. That’s gonna that’s gonna make my estrogen levels go high. And it’s not if if this is being caused by estro estrogen.

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Dr. Shawn Talbott: then, taking the women’s product will actually lower his estrogen. Because the the the the shot avari phyto estrogens will get into the estrogen receptors and block any estrogen that his body is is is over producing. But I would say I would say, just try.

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Dr. Shawn Talbott: maybe just try the men’s product, because, as test as free testosterone levels come up, it might solve whatever that monthly breakout is. That might be a. It might be a cortisol testosterone imbalance is especially especially since you mentioned stress. So I’d I’d try that. I tried. I tried men’s ignite or ignite for him. I guess it’s called for a month and see how he feels.

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Mary Nelson: Yeah, sure, that’s an interesting one, though. I’m gonna have to think about that.

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Dr. Shawn Talbott: Let me see, can antibiotics be put into hot water and drink like a tea?

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Dr. Shawn Talbott: You can.

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Dr. Shawn Talbott: But

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Dr. Shawn Talbott: all right, let me let me let me unpack this a little bit. You would not want to pour boiling water on top of antibiotics, because that boiling water would be hot enough

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Dr. Shawn Talbott: to kill the bacteria that are in there the 3 strains, strains of psychobiotic bacteria would get killed with boiling water. They wouldn’t get killed with warm water. So if you had a if you had a cup that was hot, it would. It was hot, but it was cool enough for you to drink it without burning your mouth. That would be appropriate. And so it’s. It’s maybe a pain in the butt to do this, but you would have to get the water and make sure it’s not scalding hot, and then put the antibiotics in it

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Dr. Shawn Talbott: versus doing it the other way around, you know.

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Dr. Shawn Talbott: And I missed one here. How much caffeine and pep. Oh, that’s the other we do have pep. Pep has caffeine, and I have one right here, 50 50 milligrams. So 50 milligrams here, 55 in energy, plus 100 in edge plus.

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Dr. Shawn Talbott: Okay.

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Dr. Shawn Talbott: wow, we’re getting higher on the caffeine level. What’s that? What’s that? All added up. That’s 100, and that’s 200. No.

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Dr. Shawn Talbott: to hunt. That’s 205 if you took one serving of each of those products. So you’re still within the window of

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Dr. Shawn Talbott: less than less than 400 if we’re if we’re using that as our as our ceiling.

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Dr. Shawn Talbott: Let’s see, Judy saying, just looking over the study from tonight, what are your thoughts on correlation to the barrier gut species like acrimancia? Yeah. So what I didn’t talk about, Judy? That is a great question. Versus the mechanical information as in the study. Are there any known correlation of any specific species increasing?

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Dr. Shawn Talbott: Akg. Alpha ketoglutarate that you know of in this study? They didn’t write it in their abstract but acromancia levels also went up, which suggests if Acker is going up.

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Dr. Shawn Talbott: that means that they have more mucus lining, and that means they have better gut integrity. So I think there’s absolutely a mechanical gut integrity thing going on here, as well as a metabolic thing with the indoles and the mitochondria, and all that kind of stuff. That was a really really good question, but I don’t know, like I was really surprised that Alpha Ketoglutarate was what they chose.

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Dr. Shawn Talbott: and I don’t know if if there’s

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Dr. Shawn Talbott: if there’s some other anti-aging angle that that laboratory is is is looking at. But it’d be. It’d be interesting to see, you know, to see how this, how this develops. Like I said that, like the anti-aging world in the microbiome world, are getting closer and closer and closer to each other, which is which I think is a really cool scientific development. That was, that was a nice question.

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Dr. Shawn Talbott: okay, men’s hormone question. We got it. What time are we have? Oh, it’s it’s already after 7. Okay, let me just let me see if there’s

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Dr. Shawn Talbott: if there’s anything else in here.

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Dr. Shawn Talbott: okay, I think I get everything in the chat and let me go. And, Dana, we’re gonna we’re gonna sign off with you all right. I had one last question.

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Dana Lewis: acid reflux, and you’re reaching for Pepto Bismol, or you’re reaching for Tom’s.

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Dana Lewis: Can you just unpack that for a quick. Second, why. that’s not good.

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Dr. Shawn Talbott: Yeah. So so for most people who have acid reflux or gerd gastro esophageal reflux disease like I used to have. And I’ve told. I’ve told you guys this story so for anyone who hasn’t heard this story, I used to have really, really bad, Gerd

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Dr. Shawn Talbott: and II don’t have it anymore. I haven’t had it for 7 years since we launched digestive and antibiotics, and they both work to help Gerd in different ways. So most Gerd is caused by not too much acid, but too little acid, and that sounds completely counterintuitive for someone who’s experiencing it because they’re experiencing

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Dr. Shawn Talbott: acid. It’s burning. And they. And they need to take tums or pepto, or drink water, or do something to slow to to calm the burning.

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Dr. Shawn Talbott: The 2 little acid idea is that you have food in your stomach. Your body makes a little bit of acid to start the digestive process, but doesn’t make enough to fully digest the food. And so what happens is your if your food isn’t digested, it can’t leave the stomach.

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Dr. Shawn Talbott: So the the partially digested food sits there in this bath of some acid. It’s not enough, it’s but it’s enough. It it’s not enough to digest, but it’s enough to cause burning. It’s just sitting there and like festering. In a way, it’s it sounds really, really gross.

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Dr. Shawn Talbott: The solution is to give acid. And so back in the day people would just give hydrochloric acid.

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Dr. Shawn Talbott: and that would that would stimulate the the the digestive process. The stomach would empty, the the small intestine would take over, and the the acid burning would go away. We do it now with digestive, and so we don’t just give hydrochloric acid we give, which is a which is a protease, a digest protein.

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Dr. Shawn Talbott: We give proteases and lipases which digest fat and and different. You know, Amylase, and you know different carbohydrate digesters. So you you give the different enzymes. So you’re digesting all the different kinds of food, and you

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Dr. Shawn Talbott: combine those digestive enzymes with herbal motility enhancers. So artichoke leaf and ginger root. There’s a, the combination of those is actually a patented combination that helps the stomach empty around 25% faster. And that’s enough to get that digestive process started, move all that acid stuff into the small intestine where the real digestion happens. And you’re you completely remove the

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Dr. Shawn Talbott: the, the, the burning sensations. So digestive does that from from the upper gi and pushes everything down. Antibiotics does it from the other side. If you can get the right microbiome in the lower part of the digestive tract. In a sense, you’re you’re helping the entire digestive tract. Have the right

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Dr. Shawn Talbott: environment, so to speak, in the upper, the stomach. You want to have it be really acidic in the in the middle, the small intestine. You want it to be somewhat acidic, and in the in the in the lower part of your digestive tract where the microbiome lives, you want it to be mildly acidic, and so

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Dr. Shawn Talbott: using those products in the beginning of your digestive tract, and the end of your your digestive tract helps that entire gradient of acidity. Be exactly what you want. So you have. You have good digestion. You have good absorption, and you have good microbiome.

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Dana Lewis: Would you take to digestive every day until it went away? If you’re already taking antibiotics.

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Dr. Shawn Talbott: ye yes, that’s exactly what I would do. I would start by taking 2 digestive with your largest meal, which for most people is usually dinner. And then I would take 2 digestive right before bed, and I would I would keep doing that so like. That’s that’s my regimen. I take 2 with every meal. Usually I I’m sorry. 2 with every largest meal, every dinner, and then I take 2 right before I go to bed. I don’t. I do not miss a digestive before bed. It is like it is the saving grace for

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Dr. Shawn Talbott: people with recurrent, hard heartburn. Oh, my gosh! You increase your cortisol because you increase your cord, you know it’s it’s a whole

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Dr. Shawn Talbott: metabolic cascade, just because your stomach’s not emptying, you know the way it should. So.

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Dr. Shawn Talbott: anyway. Alright, Jeanine, let’s do you let’s do you last last one? And then we’ll go. Okay. So II actually just wanted to piggyback off of that because I’ve had that all my life and really bad, so I’ve taken care of fate. I’ve taken nexium. I’ve gotten mine calm down, but my brother has been on nexium for however long nexium’s been out and has been told to stay on it. Could he do possibly digestive every day? Yeah, he has to so nexium and so blockers. And then proton pump. Inhibitors like nexium

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Dr. Shawn Talbott: are awful to be on long term. They are like, if you read the package inserts they’re 14 days no longer than 14 days, 2 weeks, and there’s people have been on them for

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Dr. Shawn Talbott: 2 years, 10 years, you know. 30 for him, I think. Yeah. And the problem with that is that what they do is they reduce the acid in your stomach. So you’re taking the problem, and you’re making it worse and worse and worse, because now you now you’re not producing acid at all. So it it’s just complete. It’s a short term effect. But and that’s I mean.

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Dr. Shawn Talbott: that’s what they’re supposed to be used for. Let’s calm the acid right now, let’s fix the problem and then let’s go off the drug. But people just go on the drug and think that that has fixed the problem. And it hasn’t. It’s actually exacerbated the problem. And your stomach isn’t emptying the way it’s supposed to. So yeah, I would get on digestive immediately, and then, as his stomach gets back into being able to produce the right way and empty the right way, he can probably start tapering himself off.

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Dr. Shawn Talbott: So do the 2 and 2. That’s exactly what it was. Yeah, but don’t. Don’t let him go cold turkey on the acid blockers. Because if you do, your acid production comes back like raging and it will, it will really really feel like he’s like he’s on fire. Okay, have him do the digestive dinner, and right before bed.

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Dr. Shawn Talbott: and have him also do antibiotics, so he gets it sort of from both ends. But then, when he’s ready. Have him taper off whatever if it’s nexium or or whatever he’s taking, have him taper off of it slowly.

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Jeanine Fusco-Lano: Okay, what is an edge that causes reflux sometimes, like Edge watermelon.

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Dr. Shawn Talbott: I don’t know. I wouldn’t think it would be anything specifically. It might just be personal sensitivity to the flavor system or something like that.

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Dr. Shawn Talbott: Yeah, but there should be.

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Dr. Shawn Talbott: Should be sometimes Gbx fit. I’m sorry. Gbx. Burn, because it has 2. Those 2 African spices can sometimes be spicy. Alright. Yeah, it’s great to see everybody. And I will.

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Dr. Shawn Talbott: Maybe next week we’ll do. We’ll do midweek or something for the webinar. Okay, alright! See you next time. Bye, bye.

About the Author

Exercise physiologist (MS, UMass Amherst) and Nutritional Biochemist (PhD, Rutgers) who studies how lifestyle influences our biochemistry, psychology and behavior - which kind of makes me a "Psycho-Nutritionist"?!?!

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